The Celebrity Mercury returned to the Port of Charleston early Thursday to disembark guests.
The cruise liner was struck again with an outbreak of the norovirus and had to return a day earlier than scheduled.
The cruise line says 364 of the vessel’s more than 1,800 passengers took ill on a cruise which left March 8.
This was the third consecutive tour where passenger were sickened with the stomach bug. Celebrity says the ship will remain in port through Sunday and extensive cleaning will again be performed.